2013

October 24^th 2013, 09:00 – 16:30

Novotel-SB1, Mainz, Germany

High Content Imaging (HCI) systems provide quantitative data from cellular assays involving automated microscopy and image analysis. These multi-parametric data sets refer to multiple endpoints and can be obtained from large numbers of cells with higher-throughput, in an observer-independent standardized way.

This information day will focus on the possibilities of the HCI technology for examination of damage mechanisms and toxic effects of chemicals. Probes for organelle and cell function and reporter systems for organ and systemic toxicity will be presented. The discussion will address questions on how phenotypic and signaling changes are linked to functional impairment and cell fate. Furthermore, the implementation of the HCI approach in (regulatory) safety sciences, latest technical advances and perspectives from the fields of systems biology/toxicology will be important topics during this event.

Time: 10:00 am – 04:00 pm

Meeting location:

Novotel Mainz

Speakers from academia, industry and regulatory agencies will include:

Dr. Mario Beilmann - Boehringer Ingelheim, Germany

Dr. Anthony Davies - Irish National Center for High Content Screening and Analysis (INCHSA), Ireland

Dr. Eugenio Fava- German Center for Neurodegenerative Diseases (DZNE), Germany

Dr. Roland Fleck - National Institute of Biological Standards and Control (NIBSC), UK

Dr. Manfred Kansky - F. Hoffmann-La Roche Ltd., Switzerland

Dr. Stefan Kustermann - F. Hoffmann-La Roche Ltd., Switzerland

Prof. Marcel Leist, University of Konstanz, CAAT-Europe, Germany

Dr. Peter Macko - European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), Italy 

Dr. William Mundy - U.S. Environmental Protection Agency (US EPA), USA

Dr. Imran Shah - National Center for Computational Toxicology, US EPA, USA

Dr. Marianne Uteng - Novartis International AG, Switzerland

Prof. Bob van de Water - Leiden University, The Netherlands